Category: Vascular Neurology

Juice ’em!

In 1995 (boy, I was 8 years old then), 3 multi-center randomized clinical trials (2 published studies) demonstrated that intravenous tissue plasminogen activator (IV tPA), when given within the first 3 hours of stroke...

Stroke and sickle cell anemia

Here are the facts: 1 in 10 children with sickle cell anemia have a stroke before college. Almost 1 in 4 children with sickle cell anemia have “silent strokes” before college. Approximately 100,000 Americans...

The many faces of PRES

Posterior Reversible Encephalopathy Syndrome Not always posterior, not always reversible, not always associated with encephalopathy. To give you the actual numbers, 75% of cases have frontal and temporal involvement, and a third affect the...

Closing the case on PFO closure

Cryptogenic stroke is the term neurologists use to describe patients with an unknown stroke etiology. (For a quick review, I’d refer you to our earlier episode on the topic.) In a large number of...